Dopamine Transporter Imaging in Psychogenic Parkinsonism and Neurodegenerative Parkinsonism with Psychogenic Overlay: A Report of Three Cases

نویسندگان

  • Chizoba C. Umeh
  • Zsolt Szabo
  • Gregory M. Pontone
  • Zoltan Mari
چکیده

BACKGROUND Differentiating psychogenic parkinsonism from neurodegenerative Parkinson's disease (PD) with psychogenic features is a diagnostic challenge. CASE REPORT We report a detailed longitudinal clinical description of three cases presenting with suspected psychogenic parkinsonism. Dopamine transporter single-photon emission computed tomography (DAT-SPECT) was used as a supplemental diagnostic study and influenced clinical management. DISCUSSION DAT-SPECT quantified the integrity of the striatal dopaminergic system in these cases of clinically uncertain parkinsonism and supported clinical decision-making.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Case Reports Dopamine Transporter Imaging in Psychogenic Parkinsonism and Neurodegenerative Parkinsonism with Psychogenic Overlay: A Report of Three Cases

Background: Differentiating psychogenic parkinsonism from neurodegenerative Parkinson’s disease (PD) with psychogenic features is a diagnostic challenge. Case report: We report a detailed longitudinal clinical description of three cases presenting with suspected psychogenic parkinsonism. Dopamine transporter single-photon emission computed tomography (DAT-SPECT) was used as a supplemental diagn...

متن کامل

Recognizing Uncommon Presentations of Psychogenic (Functional) Movement Disorders

BACKGROUND Psychogenic or functional movement disorders (PMDs) pose a challenge in clinical diagnosis. There are several clues, including sudden onset, incongruous symptoms, distractibility, suggestibility, entrainment of symptoms, and lack of response to otherwise effective pharmacological therapies, that help identify the most common psychogenic movements such as tremor, dystonia, and myoclon...

متن کامل

Doença de Parkinson: neuroimagem do transportador de dopamina em casos de dúvida diagnóstica (Resumo)

Introduction: Misdiagnosis in Parkinson’s disease (PD) can reach 25%. Recently, single-photon emission computer tomography (SPECT), using dopamine transporter (DAT) radioligands, has become useful to help diagnose clinically unclear cases of Parkinsonism (CUCP). Objectives: Study 1 reported the rationale of molecular imaging in CUCP. Study 2 evaluated the role of DAT neuroimaging in CUCP. Study...

متن کامل

Diagnoses behind patients with hard-to-classify tremor and normal DaT-SPECT: a clinical follow up study

The [(123)I]ioflupane-a dopamine transporter radioligand-SPECT (DaT-SPECT) has proven to be useful in the differential diagnosis of tremor. Here, we investigate the diagnoses behind patients with hard-to-classify tremor and normal DaT-SPECT. Therefore, 30 patients with tremor and normal DaT-SPECT were followed up for 2 years. In 18 cases we were able to make a diagnosis. The residual 12 patient...

متن کامل

Importance of proper window setting in visual assessment of dopamine transporter imaging: A case of early-onset Parkinsonism related to Park2 gene mutation

In the early stages or atypical manifestation of parkinsonism, dopamine transporter imaging can assist the early diagnosis. We describe a 19 year-old man presenting with progressive gait disturbance, cervical dystonia and head tremor. 18F-FP-CIT PET (FluoroPropyl-Carbomethoxylodopropyl-nor-BTropane positron emission tomography) was done and interpreted as normal at other hospital, and his diagn...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 3  شماره 

صفحات  -

تاریخ انتشار 2013